To start this off, I really like the colors you used. I think all the colors blend in well, but he green and pink blend together the best.
Next, the only color running down the skull's face that looks good is the red. I think that is the only color you should've had running down the skull's face, since it's the only color that would make any sense. Then it would look like the skull was bleeding and then it would have all of the rest of the colors coming out of the back of it's head, making it just look cooler and unusual. Strongly opinionated, I know, but just a suggestion.
Something I don't think a lot of people who view this will notice is all of the little details in the skull and the background. Very good job on that, but it's too bad that most of the people who view this probably won't notice that.
In conclusion, I do think this is a pretty cool painting, if a little messy.
P.S. I read your Author's Comments and I'm glad that making this painting made you feel better. I understand how you feel, when you're trying to help someone out, but you feel like you maybe made it worse. It sucks, but my advice to you is to find out for sure whether your advice to the person you were trying to help out really helped them or not. If it did, great! But if not, helping someone doesn't always work because sometimes people can only solve their problems on their own. Just remember that and hopefully, you didn't damage your relationship with that person. If you did, just say that you were only trying to help and I'm sure they'll understand. :)